Nosicielstwo i zakażenia pałeczkami z rodziny Enterobacteriaceae wytwarzającymi szeroko spektralne beta-laktamazy ESBL u pacjentów Oddziału Niemowlęcego Kliniki Pediatrii, Hematologii, Onkologii i Endokrynologii GUMed w latach 2002–2005
J. Wierzba, B. Rybak, M. Bronk, A. Samet, M. Neuman-Łaniec, A. Balcerska, B. Kaczorowska-Hać
ESBL – producing bacteria from Enterobacteriaceae family have a great capability to spread in hospital setting. Especially Klebsiella pneumoniae i Escherichia coli create an epidemiological risk both to patients (prolonged hospitalization, higher mortality, more difficult therapy due to high degree of antibiotic resistance) and to hospitals (the need of isolation, use of very expensive antibiotics in case of active infection). Among 1413 patients aged 1 day to 5 months hospitalized between 2002 – 2005 in the Department of Infant Pathology and Haemostasis Disorders, ESBL positive strains were isolated in 128 patients (9.06%). As many as 85 children (66% of ESBL positive patients) were admitted to the ward during or after a course of antibiotic treatment. In 37 cases (28.9%) multiantibiotic therapy was used. Cephalosporines were used in 46 cases. Active infection caused by ESBL positive strains was diagnosed in 31 children (24%). Performing bacteriological screening tests on the first day of hospitalization and restrictive isolation management allowed to control the endemic situation.